Article: Fos regulates neuronal activity in the nucleus accumbens.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Hu XT; Nasif FJ; Zhang J; Xu M Neurosci. Lett., 2008
Table 1Comparison of membrane properties of NAc neurons in wild-type and Fos mutant mice.
The passive and active membrane properties of medium spiny NAc neurons were measured by current clamp recordings from brain slices of wild-type and f/fc-fos-D1-cre mice. Values represent the mean±SEM for the number of neurons indicated (*p<0.05; Student's t-test). RMP: resting membrane potential; AP: action potential; AHP: after-hyperpolarization.
Group | Wild-type | Mutant |
Number of neurons | 10 | 12 |
Passive membrane properties | ||
RMP (mV) | −79.02±0.93 | −79.37±0.41 |
Rin (mW) | 128.65±24.59 | 159.17±15.90 |
Active membrane properties | ||
Current to generate AP (nA) | 0.29±0.04 | 0.20±0.01* |
AP threshold (mV) | −33.93±1.09 | −34.27±1.19 |
AP amplitude (mV) | 74.86±1.86 | 67.83±1.67* |
1/2 AP duration (ms) | 1.09±0.05 | 1.17±0.04 |
AHP amplitude (mV) | 13.51±1.05 | 9.83±0.67* |